
IndraLab
Statements
KCNH2 inhibits cholesterol. 1 / 1
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1
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"Depleting cholesterol concentration in cardiomyocytes by administration of probucol, a cholesterol synthesis inhibitor, interrupts cholesterol and caveolin -1 interaction in the plasma membrane, leading to accelerated degradation of human ether related gogo (hERG) channels, thereby prolonging action potential duration."