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MicroRNAs inhibits USP15. 2 / 2
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"Luciferase reporter assays further demonstrated that miR‐3133 mimics markedly decreased the luciferase activity of SPIN1 and USP15 3′‐UTR plasmids in AGS and HCT‐116 cells, but not that of SPIN1 and USP15 Mut‐3′‐UTR (Figure 5H)."
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eidos
"USP15 is a direct target of miR-202-5p Because we found that USP15 downregulation led to decreased apoptosis in CML cells by lowering the level of Caspase-6 protein , we sought to know whether the expression of USP15 is suppressed in CML cells by a microRNA that targets 3 ' - untranslated region ( 3 ' - UTR ) of USP15 mRNA ."
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