
IndraLab
Statements
Cholesterol inhibits NFKB1. 1 / 1
|
1
reach
"In our experiments, OX40 translocated into DIM after interaction with OX40L and although we found that the interaction between OX40 and the TRAF2-IKK compartment was independent of DIM, depletion of cholesterol or suppression of synthesis of sphingolipid and cholesterol strongly inhibited OX40 dependent NF-kappaB1 activation."