IndraLab

Statements

P5091 leads to the ubiquitination of CTNNB1. 3 / 3
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"As shown in Fig. 3 A, Myc-Ub transfection alone moderately increased ubiquitination of β-catenin, however, treatment of P5091 further enhanced β-catenin ubiquitination."
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"Likewise, addition of P5091 increased β-catenin ubiquitination ( Fig. 3 B and C)."
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"Compound P5091 enhances beta-catenin ubiquitination and degradation by inhibiting USP7, thereby inducing tumor apoptosis and inhibiting tumor growth."
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