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KCNH2 activates LQTS Type 2. 2 / 2
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"Using patch clamp to study Na + and Ca 2 + currents, as well as whole-cell current clamp to measure AP, they found that LQTS cells have tendencies toward prolonged AP duration, smaller Na + current de[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"At least three groups have studied LQTS using pluripotent cells from patients with LQTS Type 2, caused by mutations in KCNH2 (hERG channel, responsible for inwardly rectifying potassium current I Kr)."
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