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YOD1 deubiquitinates MYH9. 4 / 4
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"These results indicate that histidine at position H262 of YOD1 is involved in removing ubiquitin molecules from MYH9, thereby preventing its degradation.3.9 YOD1 regulates microglial function through deubiquitinating MYH9."
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"We demonstrate that YOD1 deubiquitinates MYH9, enhances MYH9 stability, and regulates microglial migration, phagocytosis, and inflammation regulation functions."
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"YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer's disease."
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"The results showed that YOD1 can reduce the ubiquitination of MYH9 (Fig. 7I)."
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