IndraLab

Statements


RBBP8 activates BRCC3 bound to BRCA2, RAD51, BABAM2, BRCA1, and BARD1. 1 / 1
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"DNA damage activates ATM and CHK2 kinases, which mediate phosphorylation of CtIP and BRCA1. Phosphorylated CtIP associates with BRCA1 and with the MRN complex leading to the recruitment of the BRCC complex at the site of DNA damage where HR is initiated."