IndraLab
Statements
CACNA1C activates localization. 1 / 1
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1
reach
"Co-injection of cacna1c morpholinos with either Ca V 1.2 WT cRNA (XREF_FIG) or Ca V 1.2 TS cRNA (XREF_FIG) led to rescue of contractile function in the majority of treated embryos (66.7% of cRNA rescue animals had a beating heart at 48 hpf compared with 5% of embryos treated with cacna1c morpholinos alone, P < 0.0001) suggesting proper expression, localization, and function of the rescue channels."