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[4-[[4-(1-benzothiophen-2-yl)-2-pyrimidinyl]amino]phenyl]-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone inhibits IKBKB. 1 / 3

2 | 1

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"Noteworthy, BI605906 is an IKK2-selective inhibitor , whereas IKK16 inhibits both IKK1, IKK2 as well as an unrelated leucine-rich repeat kinase 2 (LRRK2) , suggesting that IKK1 or LRRK2 could be mediating TNFα-induced SIK2 downregulation."

37386070

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IndraLab

Statements

[4-[[4-(1-benzothiophen-2-yl)-2-pyrimidinyl]amino]phenyl]-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone inhibits IKBKB. 1 / 3

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