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PTEN activates USP22. 2 / 2

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"PTEN overexpression reversed the promoting effect of USP22 knockdown on cell viability and the inhibitory effects of USP22 knockdown on apoptosis, oxidative stress, and LDH release rate in PC12 cells subjected to OGD/R."

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"Moreover, PTEN inhibition could also reverse the USP22‐mediated activation of the PI3K/Akt/mTOR pathway (Figure 5K)."

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IndraLab

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PTEN activates USP22. 2 / 2

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