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UCHL3 increases the amount of COPS5. 2 / 2
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"Furthermore, we demonstrate that UCHL3 as a deubiquitinase can deubiquitinate COPS5, thereby upregulating COPS5 levels and protein stability (Figs. 4 and 5)."

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"In summary, our results demonstrate that UCHL3 upregulates the levels of SCF beta-TrCP substrates.We have demonstrated that UCHL3 positively regulated COPS5 levels and IFNAR1 levels."