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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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TSPY1 inhibits USP7. 3 / 3

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"With this work, we reveal that TSPY1 suppresses ubiquitin specific peptidase 7 (USP7)-mediated p53 function; the promotion of spermatogonial proliferation by TSPY1 through the p53 signaling pathway probably contributes to human spermatogenesis."

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"These observations suggest that TSPY1 and TSPYL5 can induce USP7 degradation via the 26S proteasome system."

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"TSPY1 induces ubiquitin dependent degradation of USP7."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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TSPY1 inhibits USP7. 3 / 3

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