IndraLab

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BRCC3 increases the amount of NLRP6. 2 / 2
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"20 The results of this study indicate that endogenous BRCC3 siRNA significantly downregulated the protein expression of NLRP6, cleaved‐caspase‐1, cleaved‐IL‐1β, and GSDMD‐N and reduced neutrophil infiltration, thus improving neurological deficit after MCAO in mice."
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"Experiments showed that siRNA BRCC3 significantly downregulated the protein levels of NLRP6, cleavated caspase-1 and IL-1β, reduced neutrophil infiltration, and improved neurological dysfunction in MCAO mice [48]."
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