IndraLab

Statements

USP20 activates Neoplasm Metastasis. 13 / 13
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"USP20 also promotes metastasis of CRC cells and is closely correlated with several immune checkpoint genes, including ADORA2A (adenosine A2a receptor), CD160 (cluster of differentiation 160), CD27 (cluster of differentiation 27), and TNFRSF25 (TNF receptor superfamily member 25)[79]."
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"USP20 was shown to promote breast tumor metastasis, and proliferation of oral squamous carcinoma cells."
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"USP20 may promote tumor metastasis and is associated with immune infiltration and drug resistance in CRC."
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"In the metastasis assay, USP20 knockdown reduced lung metastasis, and this was reversed by YAP1 overexpression (Fig. 5G)."
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"USP20 enhances CRC cells metastasis and is associated with immune infiltration, immune checkpoints, and chemotherapy resistance."
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"Some researchers found that USP20 promotes the metastasis of breast cancer (13)."
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"USP20 promotes the metastasis of CRC cells."
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"Research has shown that USP20, a deubiquitinase, promotes breast cancer metastasis by stabilizing SNAI2 [39]."
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"Moreover, a study reported that USP20 promotes breast cancer metastasis by stabilizing the metastasis-promoting transcription factor SNAI2 (snail family transcriptional repressor 2) [52]."
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"In addition, USP20 can promote breast cancer metastasis by stabilizing SNAI2 [32]."
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"Overall, these results suggest that USP20 overexpression may promote CRC metastasis to promote cancer progression in CRC."
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"Finally, a metastasis assay revealed that USP20 depletion reduced lung metastasis (Fig. 3G)."
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"We speculate that USP20 may promote tumor progression by promoting lymph node metastasis."
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