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WRAP53 inhibits USP6. 1 / 1
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"These findings suggest that ALKBH5 inhibits GC proliferation and metastasis by downregulating WRAP53, which in turn reduces the deubiquitylation activity of USP6 on RALBP1, leading to decreased RALBP1 expression and subsequent suppression of the PI3K/Akt/mTOR pathway (Fig. 8)."