IndraLab

Statements


| 4

reach
"TREK-1 is markedly activated by clinically relevant concentrations of nitrous oxide, xenon, and cyclopropane."

reach
"There is some variation in response: the anesthetic gas N O activates TREK-1 and TRESK but not TASK-3 ; similarly, xenon and cyclopropane activate TREK-1 but not TASK-3 ; chloroform inhibits TASK-1, and halothane inhibits THIK-1 (Supplemental Digital Content, Online Supplement S2, http://links.lww.com/AA/F214, summarizes work in this area)."

reach
"Gaseous anesthetics such as xenon, nitrous oxide and cyclopropane activate TREK-1 [24]."

reach
"XREF_BIBR expressed TREK-1 channels on HEK-293 cells and showed that TREK-1 currents were enhanced by nitrous oxide, xenon, cyclopropane and halothane."