IndraLab

Statements

USP20 inhibits USP20. 3 / 3
| 3
reach
"Our findings reveal novel mechanisms regulating IL-1beta-induced proinflammatory signaling: by phosphorylating USP20 Ser334, IRAK1 diminishes the association of USP20 with TRAF6 and thus augments NFkappaB activation, SMC inflammation, and neointimal hyperplasia."
37311534
reach
"Under unperturbed condition, HERC2 ubiquitinates USP20 and promotes ubiquitination mediated proteasomal degradation of USP20, regulating the status of K48 linked polyubiquitination of CLASPIN and ensuring appropriate protein levels of CLASPIN during the S-phase."
25326330
reach
"Phosphorylation of USP20 on Ser334 substantially attenuates the anti-inflammatory activity of USP20-WT, whether USP20-WT expression is physiologic or supraphysiologic."
37311534