IndraLab

Statements

USP22 activates proteolysis. 2 / 2

| 2

reach

"Mechanistically, PRDM1 enhances USP22 transcription, thus reducing SPI1 protein degradation through deubiquitination, which enhances PD-L1 transcription."

36509766

➶

reach

"Here, by utilizing the DUB siRNA library, we found that USP22 could reduce SPI1 protein degradation through deubiquitination."

36509766

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP22 activates proteolysis. 2 / 2

INDRA sources:

Databases

Reading