IndraLab

Statements



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"The most effective of the tested compounds was TF-3, which inhibited LPS induced IKK activity by about 80%, followed by geraniin, 5GG, EGCG, TF-1, and TF-2, whereas the inhibitory effects of TR, pyroc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"As shown in [XREF_FIG], LPS induces IKKalpha and beta phosphorylaton and treatment with KOTMIN13 strongly inhibits IKKalpha and beta phosphorylaton without affecting total IKK levels."

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"LPS signals via the TLR-4 and CD14 complex and further downstream activates inhibitors of IkappaB Kinase (IKK)."

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"Moreover, LPS induced p-IKKalpha, p-IkappaBalpha, and p-NF-kappaB p65 levels were all suppressed by astaxanthin."

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"Western blot analysis showed that the level of IKK1 protein was not changed by incubation with polyphenols, suggesting that the inhibition of LPS induced IKK1 activity by the polyphenols was not due t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"