IndraLab

Statements

USP28 activates Neoplastic Stem Cells. 2 / 2
| 2
reach
"Knockdown of USP28 resulted in LSD1 destabilization, leading to the suppression of cancer stem cell (CSC)-like characteristics invitro and inhibition of tumorigenicity invivo, which can be rescued by ectopic LSD1 expression."
24075993
reach
"Although our results indicate that LSD1 is a major target of USP28 in breast cancer, it does not rule out the possibility that USP28 promotes CSC like traits through both LSD1 stabilization and inhibition of Myc degradation."
24075993