IndraLab

Statements


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"In melanoma, knockdown USP39 inhibited cell growth and induced cell cycle arrest and apoptosis."

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"In osteosarcoma cells, a decreased USP39 expression inhibited cell growth and induced apoptosis."

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"In conclusion, the inhibition of USP39 in CAL27 cells suppressed cell growth probably via induction cell cycle arrest and apoptosis."

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"These findings are in agreement with cell growth inhibition, which suggest that USP39 could modulate osteosarcoma cell growth via cell cycle control."

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"In conclusion, knockdown of USP39 by RNAi inhibited cell growth due to inactivation of the CDK1 and CyclinB complex."