IndraLab

Statements

USP39 activates cell growth. 10 / 10
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"In melanoma, knockdown USP39 inhibited cell growth and induced cell cycle arrest and apoptosis."
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"In conclusion, the inhibition of USP39 in CAL27 cells suppressed cell growth probably via induction cell cycle arrest and apoptosis."
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"In conclusion, knockdown of USP39 by RNAi inhibited cell growth due to inactivation of the CDK1 and CyclinB complex."
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"Previous studies have reported that USP39 silencing inhibits colon cancer cell growth and metastasis, and induces apoptosis by regulating the Wnt/β-catenin signaling pathway [31]."
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"These findings are in agreement with cell growth inhibition, which suggest that USP39 could modulate osteosarcoma cell growth via cell cycle control."
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"And knocking-down of USP39 and co-expression of SP1 significantly induced cell growth and proliferation compared with knocking-down of USP39 only."
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"USP39 knockdown inhibits cell growth and enhances cell apoptosis."
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"Our results suggest that USP39 condensates correlated with the expression of GLI1 and contributed to lung cancer progression by promoting cell growth and migration (Fig. 8)."
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"In osteosarcoma cells, a decreased USP39 expression inhibited cell growth and induced apoptosis."
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"Lung cancer cell growth and migration were dramatically inhibited by USP39 knockdown, which was rescued by exogenous USP39 complementation."
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