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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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TCHH inhibits COPS5. 3 / 3

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"We found that THL can inhibit Csn5 with an IC 50 of 6.2 muM (XREF_FIG)."

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"We found that THL can inhibit Csn5 with an IC 50 of 6.2 μM ( xref )."

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"Thiolutin also inhibits the JAMM metalloproteases Csn5, the deneddylase of the COP9 signalosome, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH), which regulates ubiquitin dependent sorting of cell-surface receptors, and Brcc36, a K63 specific deubiquitnase of BRCC36 containing isopeptidase complex (BRISC) and BRCA1, BRCA2, and containing complex (BRCC)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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TCHH inhibits COPS5. 3 / 3

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