IndraLab

Statements


USP18 activates JAK. 2 / 3
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"In contrast, silencing USP18 activates the Jak and STAT signaling and potentiates IFN anti-HCV ativity [XREF_BIBR]."

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"Ye et al. (2021) demonstrated that DENV-2 infection increased USP18 expression; USP18 overexpression enhanced DENV-2 replication, while USP18 silencing inhibited DENV-2 replication by activating the IFN-α-mediated JAK/STAT signaling pathway."