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YTHDF1 decreases the amount of OTUD1. 2 / 2

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"Hence, we reported that the m6A-modified mRNA of OTUD1 by METTL3 was a target of YTHDF1.Next, we transfected the METTL3 plasmid and si-YTHDF1 in AC16 at the same time and demonstrated that the elevated protein expression of OTUD1 by METTL3 overexpression could be rescued by YTHDF1 silencing (Figure 3N)."

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"YTHDF1 overexpression could restore the decreased protein expression of OTUD1 caused by silencing METTL3 (Figure S4L)."

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IndraLab

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YTHDF1 decreases the amount of OTUD1. 2 / 2

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