IndraLab

Statements

USP10 activates SKP2. 3 / 3
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"Notably, genetic or pharmacological inhibition of USP10 using Spautin-1 prominently decreased the stability of endogenous SKP2 protein, suggesting that USP10 inhibits the degradation of SKP2 in vivo."
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"USP10 modulates the SKP2 and Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia."
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"Since USP10 is a well characterized DUB in humans, exploring whether USP10 directly regulates the stability of SKP2 protein is attractive."
31044085