IndraLab

Statements

OTUB1 deubiquitinates SMAD3. 3 / 3

1 | 2

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"OTUB1 could not directly de-ubiquitinate Smad2 and Smad3, while its effect is dependent on regulating ubiquitin E2 conjugating-enzyme activity."

27604640

➶

ubibrowser

"<span class="match term0">OTUB1</span> enhances TGFbeta signalling by inhibiting the ubiquitylation and degradation of active <span class="match term1">SMAD2/3</span>"

24071738

➶

reach

"OTUB1 prevents SMAD3 ubiquitylation."

24071738

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB1 deubiquitinates SMAD3. 3 / 3

INDRA sources:

Databases

Reading