IndraLab

Statements

CYLD inhibits homeostatic process. 3 / 3
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"These findings suggest that CYLD can both positively and negatively regulate signal transduction and homeostasis of B cells in vivo, depending on the expression of CYLD splice variants."
17923499
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"At a genomic level, we established that neither TRKB and TRKC amplification, nor that of BDNF and NT3/4 was demonstrated to account for the overexpression seen in cylindroma tumours, suggesting that CYLD dysfunction perturbs normal TRK homeostasis."
21552290
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"Our data demonstrate that alterations in CYLD expression in keratinocytes disrupt normal epidermal homeostasis : the forced expression of CYLD WT in human HaCaT keratinocytes and the skin equivalents enhance keratinocyte differentiation."
21900959