IndraLab

Statements

UCHL1 activates cell growth. 4 / 4
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"UCHL1 over-expression has been reported to induce cell growth arrest in prostate cancer XREF_BIBR and breast cancer XREF_BIBR, XREF_BIBR."
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"While exploring the mechanism by which UCH-L1 promotes cell growth and survival in B-cell malignancies, we observed a striking effect of UCH-L1 on the Akt signaling pathway."
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"A role for UCHL1 in proliferation is consistent with the pro oncogenic functions of UCHL1 in various cancers [34] and the findings that in lymphoma cells UCHL1 knockdown decreases cellular growth and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"UCHL1 overexpression could induce cell growth arrest in prostate, hepatocellular and breast cancer by stabilizing p53 [16, 20, 21]."
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