IndraLab

Statements

USP47 deubiquitinates NLRP3. 3 / 3
| 3
reach
"However, it is not clear whether USP7 and USP47 directly contribute to NLRP3 deubiquitination or regulate the process somewhere upstream of NLRP3 inflammasome action [108]."
| PMC
reach
"USP47 reversed the ubiquitination of NLRP3."
35678979
reach
"Conversely, deubiquitination of NLRP3 by USP7 and USP47 positively regulates inflammasome activation and USP47 is significantly downregulated in dopaminergic neurons from idiopathic PD patient post-mortem brain samples [XREF_BIBR, XREF_BIBR]."
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