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USP25 activates TNF. 2 / 2

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"Notably, Usp21 fl/fl Lyz2-cre mice produced significantly higher concentrations of IFNbeta, IL-6, and TNF in serum upon HSV-1 infection compared with infected control mice (XREF_FIG)."

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"Consistently, Usp21 deficiency resulted in production of more IFNbeta and TNF in MEFs and BMDMs in response to HSV-1 infection (XREF_FIG)."

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USP25 activates TNF. 2 / 2

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