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Dexmedetomidine inhibits RELA. 3 / 3
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"However, small dose of dexmedetomidine did not obviously inhibit the activation of NF-kappaB p65 induced by CLP operation."
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"Our data suggest that dexmedetomidine preconditioning alleviates the degranulation of mast cells and the apoptosis of cardiomyocytes caused by I/R injury, and inhibits the activation of inflammatory related factors HMGB1, TLR4, and NF-kappaB p65."
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"Dexmedetomidine at the medium and large doses significantly attenuated activation of NF-kappaB p65 in septic rat lung."
23690665