IndraLab

Statements

Dihydroartemisinin inhibits RELA. 7 / 7
| 5 2
reach
"As shown in Figure XREF_FIG A, DHA remarkably suppressed nuclear NF-kappaB subunit p65 (also known as RelA) expression, while EPA, LA, and AA had no effect when compared to the IL-6-stimulated group."
25881314
reach
"To further determine whether p65 mediates the metastasis of normoxic CRC cells induced by HSS CRC cell-derived IL-8, we applied chemicals that specifically inhibit p65, including LY2409881 and SC-514 , and dihydroartemisinin (i.e., DHA) and SN50 ."
32737283
reach
"DHA inhibited TNF-alpha-stimulated NF-kappaB signaling, confirmed by Western blotting for IkappaB-alpha and p-p65, as well as p65 immunofluorescence."
27941926
reach
"DHA administration dose-dependently attenuated bleomycin induced upregulation of TGF-beta1, TNF-alpha, alpha-SMA, and p65 in the lungs as measured by immunohistochemical analysis, qRT-PCR, and Western blot."
33643815
sparser
"In addition, DHA inhibited nuclear p65 ( ∗ p < 0.05) ( xref ) and significantly promoted TNF- α and TRAF6 ( ∗ p < 0.05) expression with time (Figures xref and xref )."
31534470
sparser
"In addition, DHA inhibited nuclear p65 ( ∗ p < 0.05) ( xref ) and significantly promoted TNF- α and TRAF6 ( ∗ p < 0.05) expression with time (Figures xref and xref )."
31534470
reach
"Remarkably, treatment with DHA alone or DHA in combination with NAC decreased both NF-κB (p65) and NF-κB (p50) activities in LPS-stimulated cells by 1.8 and 1.6 fold for DHA alone, and 2.3 and 1.9 fol[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26079889