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MAPK3 phosphorylates USP21. 1 / 1

| 1

rlimsp

"USP21 directly interacts with NANOG through its ubiquitin carboxyl-terminal hydrolase domain (UCH), and the phosphorylation of USP21 by ERK1 prevents this binding, leaving this site exposed for ubiquitination, ultimately leading to NANOG degradation by the UPS (Jin et al., 2016)."

31428613

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IndraLab

Statements

MAPK3 phosphorylates USP21. 1 / 1

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