IndraLab

Statements


USP13 activates MTUS2. 2 / 2
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"Hence, targeting USP13 may lead to DDR deficiency and high MSI as well as activation of innate immune and antitumor immunity, and may promote a synergetic effect with DDR inhibitors and ICIs."

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"To date, no further studies have been carried out to demonstrate the potential role of USP13 in anticancer therapy, nor revealing that targeting USP13 may synergize with DDR inhibitors or ICIs."