IndraLab

Statements


BAP1 increases the amount of OGT. 5 / 6
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"BAP1 deletion has been shown to decrease the OGT and HCF1 levels, suggesting a significant role for BAP1 in stabilizing these epigenetic regulators ( Carbone et al., 2013 )."

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"BAP1 also increases OGT protein levels, suggesting that BAP1 is a potential deubiquitinase for OGT as well (XREF_SUPPLEMENTARY)."

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"In contrast, deletion of BAP1 decreases protein levels of both OGT and HCF-1 and induces MDS in mice [84] ."

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"OGT and HCF-1 levels were decreased by Bap1 deletion, and were associated with myeloid transformation ."

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"OGT and HCF-1 levels were decreased by Bap1 deletion, indicating a critical role for BAP1 in stabilizing these epigenetic regulators."