IndraLab

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SCN2A binds ERMAP and PRNP. 2 / 2

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"Even the 6-hydroxy BTA-1 derivative (also called PIB or 6-OH-BTA-1) inhibited PrP Sc formation in ScN2a cells with an IC 50 in the nanomolar range; more importantly, it has been selected for the first human trial of a benzothiazole amyloid-imaging agent [ xref ]."

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"The same group also found that rPrP-Q218K reduced PrP Sc formation in ScN2a cells."

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IndraLab

Statements

SCN2A binds ERMAP and PRNP. 2 / 2

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