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USP20 activates lipid biosynthetic process. 2 / 2

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"Besides decreasing HMGCR and lipid biosynthesis, knock-out or silencing of Usp20 led to the increase of UCP1 and energy expenditure in BAT and iWAT (Figs."

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"By contrast, USP20 inhibition promotes HMGCR degradation, reduces lipid biosynthesis, enhances succinate production, and promotes heat generation."

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IndraLab

Statements

USP20 activates lipid biosynthetic process. 2 / 2

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