IndraLab

Statements

CALM1 binds NTM. 5 / 5
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"Pull-down assays demonstrated that CaM1 was markedly bound to the NT, CT1, CT1B, PreIQ, and IQ peptides, whereas its binding to CT2, CT3, and CT1A was negligible (Fig. 5a-d)."
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"These findings indicated that CaM1 bound to both the NT and proximal CT motifs of L-VGCC."
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"Although CaM1 binding to the NT region and PreIQ tended to be decreased, while binding to CT1 and CT1B tended to be only slightly increased, CaM1 binding to the IQ domain was markedly increased in the presence of scoparone (47.06%, Fig. 6a-b)."
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"However, CaM1 binding to the PreIQ and NT peptides was not markedly affected by scoparone at total CaM1 concentrations greater than 1 μM under 1 mM Ca (Fig. S13)."
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"CaM1 binding to PreIQ and NT peptides tended to be shifted rightward by scoparone under 1 mM Ca (Fig. S13)."
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