IndraLab

Statements

Tamoxifen inhibits MAP3K7. 6 / 6
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"Tak1 gene deletion was induced by 5 consecutive day treatment of 0.5-1 mg/mouse/day tamoxifen."
20959492
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"In ER-TAK1 fl/fl mice, tamoxifen application on local skin could induce TAK1 deletion in various cell types including stromal cells, particularly cutaneous DC that are considered to play a central role for initiating response to haptens."
21552285
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"Map3k7 (f/f) Cre-ER (TM) mice (in which tamoxifen induces global TAK1 deletion) and control Map3k7 (f/f) mice were given tamoxifen at the time of unilateral ureteric obstruction (UUO) and then killed 2, 4, or 5 days later."
21367917
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"Although the role of TRAF6 in the survival of adipocytes has not been documented, a recent study has shown that tamoxifen inducible inactivation of TAK1 promotes apoptosis in adipocytes [XREF_BIBR]."
29348847
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"Similar to these findings, Sassmann-Schweda et al have recently reported that tamoxifen inducible inactivation of TAK1 causes adipocyte cell death through apoptosis [XREF_BIBR]."
29348847
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"Tamoxifen-dependent conditional depletion of TAK1 in microglial cells was induced in Cx3cr1 creER -Tak1 fl/fl mice."
32382778