IndraLab

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Hm1a activates SCN1A. 1 / 1
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"7 The Petrou group showed that application of Hm1a to mouse brain slices rescued hippocampal CA1 PV+ fast spiking interneuron function in Scn1a +/- DS mice but, surprisingly, had no effect on CA1 inhibitory neuron firing in WT littermate mice or on excitatory CA1 pyramidal neurons in DS mice."