IndraLab
Statements
Mutated BAP1 activates antigen processing and presentation. 2 / 2
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2
reach
"BAP1 mutations may inhibit the NF-kappaB signaling pathway, repressing the cytokine secretion and antigen presentation by macrophages, which induces the immunosuppressive microenvironment, enhances the malignant phenotypes of UM cells and ultimately promotes the growth and metastasis of UM."