IndraLab

Statements

Cadmium atom inhibits CYLD. 3 / 3
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reach
"These results indicate that Cd reduced CYLD availability and likely its K63 DUB function."
| PMC
reach
"We found that Cd lowered the cytosolic levels of soluble CYLD proteins and led to its accumulation in detergent-insoluble fractions (XREF_FIG A, left)."
| PMC
eidos
"In addition to aggregation , Cd induced CYLD inactivation , as shown by an increase in high molecular weight ( likely ubiquitinated ) forms of CYLD and the cleavage of CYLD into several inactive fragments of ~ 72 , 50 , and 40 kDa [ 67 ] , two events that were not recapitulated by proteasomal inhibition ( data not shown , Chargui A. IRCAN , Nice , France , 2021 ) ."
| PMC