IndraLab

Statements


Desipramine decreases the amount of KCNH2. 3 / 3
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"The pharmacological chaperone astemizole can rescue desipramine-induced impairment of fully mature hERG channel surface expression ( Staudacher et al., 2011 )."

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"XREF_BIBR, XREF_BIBR Desipramine reduces hERG expression via inhibiting trafficking and promoting endocytosis and degradation."

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"Here, we have studied in detail how desipramine inhibits hERG surface expression."