IndraLab

Statements

Dexamethasone inhibits CASP1. 3 / 3
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"Dexamethasone treatment reduced OVA-induced upregulation of NLRP3, caspase-1 and IL-1β in this model (Guan et al., 2020)."
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"However, dexamethasone does not prevent the accumulation and partial processing of caspase-1 protein or the release of cytochrome c from mitochondria."
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"In addition, caspase-1 activities were significantly reduced by AST2017-01, chrysophanol, or dexamethasone pretreatment ( Fig. 5 C, P < 0.05)."
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