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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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BAP1 activates IRF8. 3 / 3

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"We also examined whether ASXL1-MT and BAP1 upregulated posterior HOXA genes and IRF8 in human RUNX1-ETO cells by qRT-PCR."

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"ASXL1-MT and BAP1 induces upregulation of HOXA genes and IRF8."

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"In addition to posterior Hoxa genes, we found that coexpression of ASXL1-MT and BAP1 in c-Kit + cells led to upregulation of Irf8, a master regulator of monocyte differentiation, at both mRNA and protein levels 37."

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BAP1 activates IRF8. 3 / 3

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