IndraLab

Statements


BAP1 increases the amount of glutathione. 2 / 2
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"BAP1 interacts with Nrf2 to modulate SLC7A11 expression and GSH levels [116,117,118]."
| PMC

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"The expression or activity of System X is affected by epigenetics, transcription, and posttranscriptional and posttranslational regulators, such as a tumor protein p53 (p53), the nuclear factor, erythroid 2-like 2 (NFE2L2), BRCA1-associated protein 1 (BAP1), or mucin 1 cell surface-associated (MUC1), leading to complex feedback mechanisms to control GSH levels in ferroptosis (Hayano et al., 2016; Chen et al., 2017; Song et al., 2018; Zhang Y. et al., 2018)."