IndraLab

Statements

COPS5 activates HIF1A. 2 / 2

2 |

"Moreover, Jab1-enhanced transcriptional activity of HIF-1 under hypoxia led to increase the expression of VEGF, a major HIF-1 target gene. Furthermore, Jab1 increased HIF-1alpha protein levels, which was due to the enhanced HIF-1alpha stability"

11707426

➶

bel

"Jab1 acts as a cofactor to stimulate transcription of genes regulated by NFKB, AP1 and HIF1 transcription factors"

15217486

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

COPS5 activates HIF1A. 2 / 2

INDRA sources:

Databases

Reading