IndraLab

Statements

USP9X increases the amount of CCND1. 6 / 6
| 6
reach
"IHC showed that USP9X knockdown increased TUNEL expression and decreased Ki67, USP9X, CCND1, and SOX11 expression in tumor tissues (Figure 7C)."
35865393
reach
"Finally, as in HEK293 cells, depletion of USP9X increased CCND1 gene expression to levels approaching that of exogenous Wnt3a in ReNcell VM NPs."
28808228
reach
"Further, western blotting also showed that CCND1 knockdown inhibited USP9X overexpression-mediated CCND1 and SOX11 protein levels, and CCND1 overexpression promoted USP9X knockdown-mediated CCND1 and SOX11 protein levels (Figure 5C)."
35865393
reach
"28 Our study proved that USP9X overexpression promoted CCND1 expression in MCL cells."
35865393
reach
"USP9X knockdown reduced tumor volume and weight, inhibited TUNEL expression, and repressed Ki67, USP9X, CCND1, and SOX11 expression in tumor tissues."
35865393
reach
"Therefore USP9X depletion increased CCND1 expression in ReNcell VM NPs and TOPFlash induction in HEK293 cells but the effect on CCND1 was greater."
28808228