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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP9X increases the amount of CCND1. 2 / 2

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"Finally, as in HEK293 cells, depletion of USP9X increased CCND1 gene expression to levels approaching that of exogenous Wnt3a in ReNcell VM NPs."

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"Therefore USP9X depletion increased CCND1 expression in ReNcell VM NPs and TOPFlash induction in HEK293 cells but the effect on CCND1 was greater."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...