IndraLab

Statements

USP22 inhibits SIRT1. 5 / 9
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"USP22 depletion enhanced Sirt1 degradation and displayed combined effects with AGEs to further promote FN and TGF-beta1 expression."
25375034
sparser
"USP22 Inhibits SIRT1 to Regulate Ferroptosis-Induced Cardiomyocyte Death."
33192549
sparser
"Moreover, we found that USP22 inhibited the SIRT1 gene to regulate ferroptosis-induced cardiomyocyte death."
33192549
reach
"Additionally, SIRT1 instability caused by loss of USP22, a deubiquitinating enzyme that stabilizes SIRT1, is associated with the defective embryogenesis in USP22 null mice [XREF_BIBR]."
30630664
eidos
"USP22 Inhibits SIRT1 to Regulate Ferroptosis-Induced Cardiomyocyte Death A previous study has shown that USP22 possesses the ability to stabilize SIRT1 by the process of deubiquitination ( Lin et al ., 2012 ) ."
33192549