IndraLab

Statements

CTNNB1 increases the amount of UCHL1. 3 / 4
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"In the transformed cells, beta-catenin can upregulate the expression of endogenous UCH-L1 mRNA and protein [XREF_BIBR]."
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"Accumulation of stabilized beta-catenin stimulates expression of UCHL1, a marker for pulmonary neuroendocrine cells, PNECs."
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"Therefore, whether UCH-L1 expression is increased or not in HG stimulated podocytes and is mediated by Wnt and beta-catenin is not clear at present."
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